IntimaPN
Post-menopause can bring a lot of changes to a woman’s intimate area. Dryness, reduced elasticity, and discomfort during intimacy are common experiences — often caused by the thinning of vaginal tissues, a condition known as vulvovaginal atrophy.
At Prologue The Lifestyle Medical Clinic, we offer IntimaPN as a gentle, non-surgical treatment to rejuvenate vaginal suppleness – helping you regain comfort, elasticity, and confidence in your femininity.
IntimaPN is an injectable treatment designed to restore hydration and elasticity in the vaginal tissue. It stimulates fibroblasts and collagen production to support gentle, healthy tissue regeneration.
This treatment is especially beneficial for women experiencing symptoms of vulvovaginal atrophy, such as dryness, irritation, or painful intercourse. By improving tissue quality, it helps women regain their confidence and vitality.
IntimaPN combines three key ingredients, including polynucleotides (PN-HPT®), hyaluronic acid, and mannitol, to deliver its rejuvenating effects. Here’s how each molecule works:
- Polynucleotides (PN-HPT®): Extracted from purified DNA fragments of trout fish, this patented biopolymer stimulates fibroblast activity, supporting collagen and elastin production to aid tissue repair and regeneration.
- Hyaluronic acid: A water-binding molecule that provides deep hydration, improving firmness and suppleness in the intimate area.
- Mannitol: A potent antioxidant that helps stabilise hyaluronic acid, prolonging its hydrating and protective effects.
Benefits of IntimaPN
59%
Improvement in vaginal dryness
54%
Reduction in irritation
59%
Improvement in dyspareunia (pain during intercourse)
76%
Reduction in itching
70%
Reduction in pain and tingling
Results may vary. Improvements were reported after the completion of 5 IntimaPN sessions.
Am I Suitable for IntimaPN?
IntimaPN is suitable for almost all women with symptoms of vulvovaginal atrophy, such as dryness, irritation, or painful intercourse.
Whether you wish to ease the discomfort or rekindle intimacy that’s been missing, IntimaPN offers a gentle, non-invasive solution to help you feel comfortable and like yourself again.
However, IntimaPN should be postponed or avoided with the following conditions:
- Active infection
- Abnormal Pap results
- Pregnancy
- Cancerous or tumour growths in the reproductive system
- Allergies to Polynucleotides, hyaluronic acids, or mannitol
- Bleeding disorders
A consultation and medical screening are required to determine your suitability. If any of the conditions listed above are detected, our doctor can help find a more suitable therapy option.
What Does an IntimaPN Treatment Look Like?

Pre-Treatment
- Consultation: You’ll speak with our team about your concerns, such as vaginal dryness, irritation, painful intercourse, and other related issues.
- Health Screening: Our team will conduct a thorough health assessment, including a Pap, cervical, and other necessary assessments to determine your eligibility.

During Treatment
- Numbing cream application: A topical anaesthetic will be applied to ensure your comfort during the IntimaPN injections.
- Injection: IntimaPN will be injected into the vaginal walls and labia.
- Duration: The procedure is quick, taking about 30 – 45 minutes.

Post-Treatment
- You may experience temporary side effects such as mild redness, swelling, or sensitivity for a few hours after the procedure.
- Avoid intercourse for at least 72 hours.
- Follow the recommended course of 2–5 sessions for optimal results.
- Schedule touch-up maintenance every 6–12 months.
Is IntimaPN Safe?
Yes, IntimaPN is safe. Its ingredients, including polynucleotides, hyaluronic acid, and mannitol, are the result of decades of research and have been clinically proven to improve symptoms of vulvovaginal atrophy, particularly among postmenopausal women.
For safety reasons, the treatment must be performed by a licensed medical doctor, who will conduct a thorough health screening and ensure the following requirements are met:
- No underlying conditions that determine ineligibility
- Use of sterile techniques
- Careful attention to injection depth to avoid deeper tissues or organs
After the procedure, you may experience temporary side effects such as mild redness, swelling, or sensitivity lasting for a few hours or days.
Rare risks like bleeding, infection, lumps, or allergic reactions can be further reduced through proper pre-treatment screening.
Comparing IntimaPN with Other Vaginal Rejuvenations
IntimaPN is one of the vaginal rejuvenation treatments available at Prologue The Lifestyle Medical Clinic, focusing on restoring hydration and elasticity. Another option, IntimaLase®, offers similar rejuvenating benefits but primarily targets vaginal laxity.
IntimaLase® is a non-invasive, laser-based treatment designed to tighten and strengthen vaginal tissue. The laser delivers controlled thermal energy that stimulates collagen remodelling and the formation of new fibres for improved firmness.
This laser treatment is beneficial for women experiencing vaginal laxity after childbirth or due to natural ageing, helping them feel more confident and supported again.
IntimaPN | IntimaLase® | |
Method | Injections | Er:YAG Laser |
Recommended for | Symptoms of vulvovaginal atrophy: dryness, irritation, dyspareunia, itching, and pain or tingling | Vaginal laxity |
Sessions | 2-5 sessions for optimal results | 1-3 sessions for optimal results |
Maintenance | Every 6-12 months | Once a year |
Downtime | Minimal | Minimal |
In some cases, where both vaginal dryness and laxity are present, a combination of IntimaPN and IntimaLase® may be recommended. A consultation with our doctor will help determine the most suitable approach for your specific concerns.
It’s also important to note that both IntimaPN and IntimaLase® are non-surgical rejuvenation treatments designed for mild to moderate symptoms. For severe vaginal laxity or prolapse, surgical options may still be necessary for optimal correction.
How Much Does IntimaPN Cost?
In Singapore, IntimaPN typically costs between $200 and $400 per session. The exact price may vary depending on the clinic. Package options are often available at more affordable rates.
Also consider additional costs such as consultation fees, numbing cream, and disposable materials that may apply.
For an accurate estimate, it’s best to speak with our team. We can provide a personalised quote based on your goals and treatment plan.
Rediscover Your Comfort and Confidence
Experiencing symptoms of vulvovaginal atrophy is common, especially after you hit postmenopause. But it doesn’t mean you should be ignoring vaginal dryness, irritation, or painful intercourse up to the point it starts affecting your comfort and confidence.
Feel like yourself again with IntimaPN – a gentle, non-surgical solution to rejuvenate vaginal suppleness, helping to bring back your vitality for once more.
FAQ
How soon will I feel improvement?
Results will vary from one individual to another. However, most patients notice improvements in about 1 – 3 months after completing the course of treatment.
How many sessions are needed?
Depends on your conditions. We usually recommend between 2-5 sessions for optimal results.
Is it painful?
For some, the injections can feel uncomfortable. We’ll apply a topical anaesthetic to reduce the discomfort.
How long do results last?
Depends on each individual. Usually, results can last 6 – 12 months, and may be repeated to maintain results.
Can I combine it with other treatments?
Yes, in some cases, a combination with other vaginal rejuvenation procedures may be recommended. Consult our doctor for more details.
Is there downtime?
Downtime is minimal. You may experience mild redness, swelling, or sensitivity that lasts for a few hours or days. You also need to abstain from intercourse for at least 72 hours.
What if I’m postmenopausal?
IntimaPN is designed for women experiencing vulvovaginal atrophy, including those who are postmenopausal. As long as you’re healthy and our doctor has confirmed your eligibility, IntimaPN is safe for you.
Is it safe after childbirth?
Yes, it is safe once your body has fully recovered from childbirth.