Shingrix
Shingrix provides robust immunity against the varicella-zoster virus (VZV), which causes shingles (herpez zoster). It also helps prevent associated complications, including post-herpetic neuralgia (PHN).
Shingrix delivers efficacy rates exceeding 90% in individuals aged 50 and above.
The Shingrix vaccine is administered in two doses, spaced two to six months apart, ensuring long-lasting protection for up to 10 years. It is recommended for adults aged 50 and older, as well as individuals aged 18 and older with weakened immune systems. Vaccinating with Shingrix significantly reduces your risk of developing shingles and its often excruciating complications.
What is Shingles?
Shingles, or herpes zoster, is a condition caused by the reactivation of the varicella-zoster virus, the same virus responsible for chickenpox. Even after recovering from chickenpox, the virus remains dormant in the body’s nerve cells and can reactivate later in life, particularly when the immune system weakens and ages.
Nearly 99.5% of adults aged 50 and older already carry the varicella-zoster virus. The likelihood of reactivation increases significantly with age, and in Singapore alone, approximately 30,000 new cases of shingles are reported annually. Globally, shingles affects millions of people, with rates rising steeply in individuals over 50.
Shingles is more than just a rash; it can cause severe burning pain, long-lasting nerve damage, and complications that drastically impact your quality of life. Without vaccination, individuals face a high risk of developing this distressing condition. The pain from Shingles can be intense, and complications can severely limit daily activities and overall well-being.
What are the Symptoms of Shingles?
1
Burning or tingling pain
Often the first sign of shingles, this pain can be intense and persistent.
2
A red rash with fluid-filled blisters
Appears on one side of the body or face, usually along a nerve pathway.
3
Blistering and scabbing
The blisters dry and crust over within 7-10 days.
Additional symptoms: Some individuals may experience fever, chills, headache, or upset stomach.
1 in 3 people will develop shingles in their lifetime.
While Shingles can last a matter of 2 to 4 weeks for some, complications like post-herpetic neuralgia (PHN) may cause persistent pain for months or even years.
In Singapore, shingles prevalence is particularly high among older adults with weakened immune systems, making early vaccination crucial. Those with diabetes mellitus are at 19% increased risk of PHN, and 63% increased risk of Shingles-related hospitalisation
What are the Complications That Arise from Shingles?
Shingles can lead to several severe complications, including:
- Post-Herpetic Neuralgia (PHN): A chronic nerve pain that affects up to 30% of shingles patients and can last for months or years.
- Vision loss: If shingles occurs around the eyes (herpes zoster ophthalmicus), it can result in permanent vision damage.
- Neurological issues: Depending on which nerves are affected, shingles can cause encephalitis or hearing loss.
- Skin infections: Blisters may become infected, leading to scarring.
- Cardiovascular risks: Shingles has been linked to an increased risk of stroke and heart attack.
The pain and complications from shingles can be severe enough to impact one’s quality of life significantly, affecting sleep, work productivity, and emotional well-being.
Who is at Risk of Shingles?
Certain factors increase the risk of developing shingles, including:
- Age: Individuals over 50 are at the highest risk, with 99.5% of adults in this age group carrying the dormant varicella-zoster virus.
- Weakened immune systems: Those with conditions like diabetes, cancer, or HIV or those taking immunosuppressive medications.
- Stress: High stress levels or recent surgical procedures can trigger shingles.
- Family history: A genetic predisposition may play a role in shingles susceptibility.
- Global impact: Shingles affects roughly 30,000 individuals in Singapore and an estimated 1 million in the United States, 1.7 million in Europe and 1.5 million in China yearly.
- Diabetes mellitus: Patients with diabetes have a 38% increased risk of developing shingles compared to those without.
How Effective is Shingrix?
Shingrix offers 89% efficacy for up to 10 years post-vaccination. While efficacy slightly decreases with age, it remains highly protective across age groups:
- Ages 50-59: 96.6% efficacy
- Ages 60-69: 97.4% efficacy
- Ages 70-79: 91.3% efficacy
- Ages 80+: 91.4% efficacy
Getting vaccinated early ensures you can enjoy robust protection for years to come, giving you peace of mind and greater control over your health.
How Does Shingrix Vaccination Look Like?
Shingles is a serious health condition that can affect anyone who has had chickenpox, particularly individuals 50 years old and above. Even if you consider yourself healthy, the risk remains, making prevention essential.
Shingrix offers an effective, long-lasting solution to protect against shingles and its complications. Speak to your doctor today to discuss whether Shingrix is the right choice for you. Take control of your health and protect yourself against shingles.
Conclusion
Shingrix offers protection against shingles and its complications by boosting your immune response to the varicella-zoster virus, significantly reducing the likelihood of virus reactivation. Shingrix provides over 90% efficacy in preventing shingles across all age groups above 50.
Moreover, Shingrix is effective in reducing the risk of post-herpetic neuralgia, a debilitating condition that often follows shingles. By getting vaccinated, you protect yourself from physical pain and safeguard your quality of life.
FAQ
Who is Shingrix recommended for?
Shingrix is recommended for adults aged 50 and older, as well as individuals aged 18 and older with weakened immune systems.
How many dosages of Shingrix do I need?
You need two doses, spaced two to six months apart.
How long does the vaccination last?
Shingrix provides robust protection for at least four years post-vaccination.
When should I go for my second dose of Shingrix?
Your second dose should be scheduled two to six months after the first dose.
What are the possible side effects of Shingrix?
Common side effects include pain at the injection site, fatigue, headache, and mild fever.
How painful is shingles?
Shingles pain is often described as severe, burning, or excruciating.
If I already have shingles, can I still be vaccinated with Shingrix?
Yes, Shingrix can still be administered after a shingles episode to prevent future occurrences.
Will shingles go away on its own?
- Shingrix is recommended for adults aged 50 and older, as well as individuals aged 18 and older with weakened immune systems.
Can I get Shingrix if I've been vaccinated for chickenpox?
Yes, Shingrix is still recommended for those vaccinated for chickenpox, as the varicella-zoster virus can reactivate later in life.
